×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Here we tested the performance of the Ion Torrent PGM platform with the Ion AmpliSeq BRCA1 and BRCA2 Panel in our clinical routine of breast/ovarian hereditary cancer syndrome assessment.
31065452 2019
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.
29446198 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Characterization of mutations in BRCA1/2 and the relationship with clinic-pathological features of breast cancer in a hereditarily high-risk sample of chinese population.
29435039 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
BRCA1 and BRCA2 mutation spectrum - an update on mutation distribution in a large cancer genetics clinic in Norway.29339979 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 mutation spectrum - an update on mutation distribution in a large cancer genetics clinic in Norway.29339979 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study.
29337092 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 germline variants in breast cancer patients from the Republic of Macedonia.
29335924 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
High prevalence of deleterious BRCA1 and BRCA2 germline mutations in arab breast and ovarian cancer patients.
29297111 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Lynch syndrome and BRCA-1 and BRCA-2-associated hereditary breast and ovarian cancer are hereditary cancer syndromes frequently involving the gynaecological tract but tumours associated with similar molecular alterations may also occur sporadically.
29287922 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Genetic and clinical characteristics in Japanese hereditary breast and ovarian cancer: first report after establishment of HBOC registration system in Japan.
29176636 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
The yield of targeted genotyping for the recurring mutations in BRCA1/2 in Israel.
29086229 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
"Mutational spectrum in breast cancer associated
29021639 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Mutations in BRCA1, BRCA2 and other breast and ovarian cancer susceptibility genes in Central and South American populations.
28985766 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
The frequency of cancer predisposition gene mutations in hereditary breast and ovarian cancer patients in Taiwan: From BRCA1/2 to multi-gene panels.
28961279 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Hypoxia-Activated Alkylating Agents in BRCA1-Mutant Ovarian Serous Carcinoma.
28959512 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Mutations in context: implications of BRCA testing in diverse populations.
28918466 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers.
28831036 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Gene-panel testing of breast and ovarian cancer patients identifies a recurrent RAD51C duplication.
28802053 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance.
28781887 2016
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance.
28781887 2016
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Preoperative Panel Testing for Hereditary Cancer Syndromes Does Not Significantly Impact Time to Surgery for Newly Diagnosed Breast Cancer Patients Compared with BRCA1 /2 Testing.
28766202 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients.
28724667 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Prevalence and spectrum of germline rare variants in BRCA1/2 and PALB2 among breast cancer cases in Sarawak, Malaysia.
28664506 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers.
28637432 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Chemosensitivity of BRCA1-Mutated Ovarian Cancer Cells and Established Cytotoxic Agents.
28604461 2017